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PT-141 10mg
PT-141 (research-use-only) is a synthetic melanocortin-derived peptide studied as an agonist of MC3R/MC4R in models of GPCR signaling, neuromodulatory network mapping, and stress-adaptation pathways. Not intended for diagnostic or therapeutic use.
MC3R/MC4R pathway activation and receptor cross-talk profiling
Calcium flux, cAMP reporter assays, and downstream kinase-cascade readouts
In vitro neuroendocrine and stress-response dynamics
BAC Water Sold Separately - Syringes Not Included | Peptides sold in powdered form.
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*Disclaimer:
This product is intended solely for laboratory research purposes. It is not suitable for consumption by humans, nor for medical, veterinary, or household purposes. Researchers should handle Agomelatine with care and adhere to strict safety guidelines during experiments. Kindly review our Terms & Conditions before making a purchase.
Description
Signal transduction peptides are used in RUO studies to explore how cells send and receive messages. These tools help researchers dissect receptor activation, second-messenger dynamics, and downstream transcriptional programs.
PT-141, also called Bremelanotide (generic clinical name), is a heavily modified synthetic derivative of alpha-melanocyte-stimulating hormone. It has been tested in clinical trials as a treatment for both male/female hypoactive sexual desire disorder and acute hemorrhage. PT-141 is an agonist for the melanocortin-4 and melanocortin-1 receptors.
Chemical Class:
Synthetic heptapeptide analog of α-MSH (melanocortin peptide)IUPAC Name (peptide form):
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OHPeptide Sequence (cyclic):
Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH
(Cyclized through Asp–Lys side-chain lactam bridge)Molecular Formula:
C₅₀H₆₈N₁₄O₁₀Molecular Weight:
≈ 1025.2 g/molStructural Features:
Heptapeptide
N-terminal acetylation
Side-chain lactam (Asp–Lys) macrocycle
Contains non-canonical amino acids: Nle (norleucine) and D-Phe
Designed for high affinity and selectivity toward MC3R and MC4R receptors
This product is intended solely for laboratory research purposes. It is not suitable for human, animal, or household use. Researchers must follow institutional safety protocols. See our Terms & Conditions and our Research Compliance Disclaimers for details.
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